Analysis of avian disease transmission risk and prevention measures in China

Many zoonotic diseases are found in wild animals and present a serious risk to human health, in particularly the virus carried by birds flying freely around the world is hard to control. There are three main bird migration routes which cover the most areas of China. It is important to investigate and fully understand the types of avian transmitted diseases in key areas on the bird migration routines and its impacts on both birds and human health. However, no literature is available in how about the risk of virus carried by migrating birds, and how to predict and reduce this risk of virus spreading to human being so far. In this paper, we first reviewed the main pathogen types carried by birds, including coronaviruses, influenza viruses, parasites, Newcastle disease virus (NDV), etc., and then discussed the spread risk of avian viruses to human being and animals in key areas of biosafety prevention. We also analyzed and discussed the risk of cross-spread of diseases among different bird species in nature reserves located on bird migration routes which provide sufficient food sources for migratory birds and attract numerous birds. Diseases transmitted by wild birds pose a serious threat to poultry farms, where high density of poultry may become avian influenza virus (AIV) reservoirs, cause a risk of avian influenza outbreaks. Airports are mostly built in suburban areas or remote areas with good ecological environment. There are important transit places for bird migration and densely populated areas, which have serious risk of disease transmission. Finally, this paper puts forward the following prevention suggestions from three aspects. First, establish and improve the monitoring and prediction mechanism of migratory birds, and use laser technology to prevent contact between wild birds and poultry. Second, examine and identify virus types carried by birds in their habitats and carry out vaccination. Third, protect the ecological environment of bird habitat, and keep wild birds in their natural habitat, so as to reduce the contact between wild birds and human and poultry, and thus reduce the risk of virus transmission.

Susceptibility of domestic and wild animal species to SARS CoV-2 naturally infection (review)

Severe acute respiratory syndrome coronavirus (SARS-CoV-2), the causative agent of the current COVID-19 pandemic, has evolved to have a wide range of hosts, including non-human primates, wild and domestic animals. Determining the susceptibility of different animal species to SARS-CoV-2 infection and the role of animals in the epidemiology of the disease will be critical to designing appropriate human and veterinary public health responses to this pandemic. A better understanding of the susceptibility of animal species to SARS-CoV-2 may help clarify transmission mechanisms and identify potential reservoirs and sources of infection that are important for both animal and human health. The current pandemic produced by SARS CoV-2 and its variants represents an example of the unique concept of health (One Health) in which humans and animals are components of the same epidemiological chain. In this paper, only the natural infections found in different animals species will be reviewed, according to literature data, regarding the species of affected animals, the transmission patterns (human-animal, animal-human), clinical aspects, diagnosis confirmation and a brief presentation of the prevention possibilities through vaccination.

Animal diseases - current developments

The health of domesticated animals and wild animals is frequently threatened by animal illnesses. It typically receives less attention and information than illnesses that also impact humans, including the Corona virus. To be able to respond quickly, it is crucial to understand the epidemic's progression and transmission vectors. Numerous new diseases have been reported in the news over the past 20 years, the majority of which having an animal source (zoonoses). Examples from recent times include the West Nile virus, SARS, avian influenza, and monkeypox. Some developing diseases impact both humans and animals, whereas others only affect either animals or humans. All of these emerging or reemerging illnesses, however, have societal repercussions that are frequently connected to regional and global economy. Understanding the effects of newly emerging animal diseases is crucial, as is promoting closer veterinarian and medical professional collaboration, particularly in rural regions. The index cases for newly developing diseases may be illnesses that affect agricultural laborers.

Game meat procurement market in Poland in 2009-2021

Procurement of game animals is a major source of revenue for hunting clubs in Poland. For several years, the game meat buying market has been showing an upward trend, but this situation is also influenced by random factors that negatively affect the value of the game meat buying market. For several years in our country we have been struggling with the ASF virus, and since 2020, negative effects in the economy related to the occurrence of the SARS-CoV virus have been observed, also affecting the hunting sector with its activities. The aim of the study was to analyze the dynamics of game meat procurement in Poland in the years 2009-2021. The data concerned the three most important species, namely deer, roe deer and wild boar. The analysis covered the quantity of game meat, procurement value and the average price of game meat depending on animal species. The conducted research confirmed an upward trend in the volume and value of game meat procurement for all the analysed game species. Similarly, the average procurement prices of roe dee and wild boar meat with the exception of red deer, showed an upward trend. The study confirmed the negative impact of the ASF virus and the SARS-CoV-2 virus on the game meat buying market in Poland.

Risky business: how Peru's wildlife markets are putting animals and people at risk

This publication presents Peru's illegal wildlife trade activity before and after Covid-19 pandemic which creates a perfect conditions for zoonotic emerging infectious diseases such as SARS-CoV-2 to emerge and spread among animals and people, thus recommendations to prevent this scenario are highlighted.

World forests, global change, and emerging pests and pathogens. (Special Issue: Re-assessing the challenges of emerging pests and pathogens for sustainable development post-COVID.)

Global changes play today an important role in altering patterns of human, animal, and plant host-pathogen interactions and invasive pest species. With rapid development in sequencing technology, there is also an increase in pathogen and pest studies adopting a macroscale, biogeographical perspective, and we present the most recent elements on existing ecological and biogeographical trends. We also compare the results on the one hand on emerging infectious diseases of animals and humans, and on the other hand on plant pathogens and pests. International exchanges of people, animals, and plant products currently contribute to their geographical extension but with notable differences across disease and pest systems, and regions. This review highlights that the subject of pathogens and plant pests, traditionally rooted in agronomic approaches, lacks work on macroecology and biogeography. We discuss the research orientations to better anticipate their ecological and economic impacts in order to better achieve environmental sustainability.

Infectious disease Roundup 2022

This paper describes the epidemiology, prevalence, transmission, prevention and control of some infectious diseases in companion animals, livestock, wild animals and humans in Ontario, Canada, in 2022, including SARS-CoV-2;Echinococcus multilocularis, Leishmania spp. and SARS-CoV-2;antimicrobial stewardship resources;2 cases of rabid dogs imported from Iran (July 2021 and January 2022);prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriacea, Dirofilaria immitis, Brucella canis, canine parainfluenza and adeno- and herpes viruses in dogs recently imported from Asia;Paragonimus kellicotti lung flukes and Streptococcus equi subsp. zooepidemicus in dogs;African swine fever in pet pigs, backyard pigs and wild pigs and blastomycosis in dogs and humans.

Fostering landscape immunity to protect human health: a science-based rationale for shifting conservation policy paradigms

Anthropogenic land use change is a major driver of zoonotic pathogen spillover from wildlife to humans. According to the land use-induced spillover model, land use change alters environmental conditions that in turn alter the dynamics between zoonotic pathogens and their wildlife hosts. Thus, in response to the global spread of the SARS-CoV-2 virus (the agent of COVID-19 disease), there have been renewed calls for landscape conservation as a disease preventive measure, including by the G7 Ministers responsible for Climate and the Environment. Landscape immunity, as a new construct, points to four paradigm shifts the world must favor to effectively mitigate pandemic risks. We provide a landscape immunity primer for policy makers and make the case for "world views" that place Homo sapiens within ecological systems, regard human health as an ecological service, prioritize investments in prevention, and apply ecological restoration to human health goals. Crisis is a conversation starter for reimagining and recommitting ourselves to what is most vital and generative. We urge world leaders to make the move to a nature-positive world.

Susceptibility of different animal species to experimental infection with SARS-CoV-2 (review)

The susceptibility of animal species to SARS-CoV-2, under experimental conditions, is a subject of great interest for the international scientific community. Compared to observational studies of natural disease outbreaks in different animal species, experimental studies based on in silico, in vitro and in vivo research, are important alternatives to evaluate the prediction of potential hosts for SARS-CoV-2 infection. In order to determine the susceptibility of a host species and the risk of acting as a potential animal reservoir, a large number of different animal species, domestic and wild, were experimentally infected with SARS-CoV-2, which were classified as permissive or resistant. Experimental infections have proven to be crucial for clarifying aspects of the pathogenetic mechanism, viral persistence and elimination, immune response, antiviral sensitivity, vaccine production, immunotherapy and improving diagnostic methods. In this article, some experimental infections carried out in different animal species will be reviewed, according to the data from the literature.

The impact of reproductive disorders in animals infected with the SARS-CoV-2 virus: a literature review

The COVID-19 pandemic caused by the SARS-CoV-2 virus has spread worldwide since the end of 2019. This virus infects humans and has also been found to infect animals. Viruses enter the human body through the ACE2 receptor on apical epithelial cells. ACE2 receptors are also present in animal epithelial cells, so the possible effects of cell damage due to SARS-CoV-2 infection in humans can also occur in animals. However, studies on the long - term effects of SARS-CoV-2 infection in animals, especially fertility, have not been widely reported. Therefore, this literature review aims to identify and analyze the long-term effects of SARS-CoV-2 virus infection on the function of the reproductive system of animals, especially protected wildlife. The data were obtained from literature published in PubMed-gov with selected keywords and several other filters activated. The study result s indicate that there is a possibility that animals infected with the SARS-CoV-2 virus could cause infertility, so the application of health protocols is important for people who are in close contact with animals, especially wild animals.

Prospect of Vaccinia virus vector vaccine for wildlife

Against a pandemic of emerged infectious disease, COVID-19, new generation vaccines based on nucleic acids or recombinant viruses, which had not been used as vaccines in humans, have been inoculated and shown to be successful. They are, however, heat-labile and need a cold-chain including deep-freezers for storage and transportation. Vaccinia virus (VAC) vector vaccine (VACV) is a pioneer of new generation of vaccines constructed by using molecular biological technology. VACV, which has contributed to eradication of smallpox, has excellent characteristics of vaccinia virus such as a high heat-stability and long-lasting immunological effects. It is possible to distinguish the immunological responses of vaccination from those of natural infections. We started our developmental researches 35 years ago, using attenuated VAC strains established in Japan. In this article, we first describe the early researches of VACVs;development of two VACVs for Bovine leukemia virus and Rinderpest morbillivirus antigens and their protective immunity in large mammals, sheep and cows. Second, application of VACV is described;Rabies-VACV, which has already been licensed, used in the field in Europe and USA, and resulted in a prominent decrease of rabies. Then, current status of VACV research is described;non-replicating VACVs in mammalian cells have been developed as new-generation and ultimately-safe vaccines. We discuss the possibility of future application of VACV for wildlife.

Fumbling out the effective pathways to apply the wildlife and forest analytic toolkit in the Mekong region: looking at data and analysis perspectives

The Wildlife and Forest Analytic Toolkit, introduced by the International Consortium on Combating Wildlife Crime (ICCWC), is designed to increase the effectiveness of measures combating wildlife and forest crimes (WAFCs). Greater Mekong Subregion (GMS) countries have applied this toolkit as one of their priority actions after recognizing concerns about the biodiversity system and conservational zone through several illegal wildlife trade (IWT) activities. Although the toolkit has realized its fundamental objectives to readjust legal frameworks, enhance enforcement involvement, and improve their judicial and prosecutorial operations, the last components of data and analysis have not yet been implemented. This leads to slow updates of both trends and patterns concerning WAFCs that raise questions about the real levels of exploitation in the region. Using gray literature with published materials, combined with the IWT's database in the CITES system, this study examines why the data and analysis component of the Toolkit created obstacles in the GMS countries. Findings point to there being at least four main challenges to implementing data and analysis as the toolkit has recommended in the region: (1) availability and reliability of data;(2) data collection;(3) data resources (internal vs. external level);and (4) analytic research and its related monitors. Some practical recommendations call for further discussions. Meanwhile, updated information and specific data relating to zoonotic disease transmission are timely, considering the coronavirus pandemic.

Wild goose chase: Geese flee high and far, and with aftereffects from New Year's fireworks

In the present Anthropocene, wild animals are globally affected by human activity. Consumer fireworks during New Year (NY) are widely distributed in W-Europe and cause strong disturbances that are known to incur stress responses in animals. We analyzed GPS tracks of 347 wild migratory geese of four species during eight NYs quantifying the effects of fireworks on individuals. We show that, in parallel with particulate matter increases, during the night of NY geese flew on average 5–16 km further and 40–150 m higher, and more often shifted to new roost sites than on previous nights. This was also true during the 2020–2021 fireworks ban, despite fireworks activity being reduced. Likely to compensate for extra flight costs, most geese moved less and increased their feeding activity in the following days. Our findings indicate negative effects of NY fireworks on wild birds beyond the previously demonstrated immediate response.

COVID-19 lockdowns promoted recovery of the Yangtze river's aquatic ecosystem

The impacts of COVID-19 lockdowns on human life, air quality, and river water quality around the world have received significant attention. In comparison, assessments of the implications for freshwater ecosystems are relatively rare. This study explored the impact of COVID-19 lockdowns on aquatic ecosystems in the Yangtze River by comparing river water quality, phytoplankton, zooplankton, and fish data collected at the site in the middle reach of the Yangtze River in 2018 and 2020. The results show that during COVID-19 lockdowns, the reduction in industrial and domestic effluent discharge led to a reduction in organic pollution and industrial plant nutrient pollution in rivers. Among them, PO43--P, CODMn, and TP were significantly decreased (p < 0.05). During lockdowns, nutrient supplies such as TN and TP were reduced, which led to inhibition of algae growth and decreased phytoplankton abundance. Phytoplankton affects the abundance of zooplankton through a bottom-up effect, and a decrease in phytoplankton density leads to a decrease in zooplankton density. The decrease in plankton density led to lower primary productivity in rivers, reduced fish feed supplies, intensified competition among fish populations, with increases in population dominated by high trophic level carnivorous fish. In addition, the decrease in fishing intensity has contributed to an increase in the number of rivers-sea migratory fish;the fish community was earlier mainly dominated by small-sized species with a short life cycle, and the number of supplementary populations has now increased. As a consequence, the fish community structure shows a tendency toward high complexity and high fish diversity. Overall, these observations demonstrate that the rapid revival of the retrogressive Yangtze River ecosystem is possible through limitation of anthropic interferences.

Possession of exotic animals and zoonotic diseases: an approach from the Mexican context

The possession of exotic animals as pets is a social practice that has become more visible in Mexico in recent years, so it is interesting to understand its environmental and social implications and those related to human health. The present study aims to identify the main species of exotic animals kept as pets and the zoonotic diseases reported in these species. We analyzed official figures of seizures of exotic fauna in Mexico and reviewed specialized literature on zoonotic diseases documented in Mexico in these species. We identified zoonoses in species of fauna that can be acquired legally and illegally in the country, reported in environments in which animals coexist with other species and are in direct contact with people, which represents an important factor in the spread and propensity of this type of disease. We conclude that the sanitary regulation of wildlife markets, the monitoring and studying microorganisms associated with wildlife are valuable strategies to prevent the emergence of zoonoses.

SARS-CoV-2 in animals used for fur farming: GLEWS+ risk assessment (20 January 2021)

SARS-CoV-2 was first identified in humans in December 2019 and has since affected almost 68 million people causing over 1.5 million deaths worldwide. Animal-to-human and animal-to-animal transmission has been documented within farmed minks in several countries. SARS-CoV-2 has been identified in a farmed mink population in a number of countries. Some of the affected farms reported also workers SARS-CoV-2 infection and it is hypothesized that the mink farms were infected through human-mink transmission proving SARS-CoV-2 capability of reverse zoonosis. This Tripartite Risk Assessment, as a joint effort under the GLEWS+ initiative, completed with the Food and Agriculture Organization (FAO), the World Health Organization (WHO), and the World Organisation for Animal Health (OIE), evaluates the risk of introduction and spread of SARS-CoV-2 within fur farming systems as well as whether farmed fur animals could play a significant role in the spread of SARS-CoV-2 to humans via spillover. Additionally, using a One Health approach, the Tripartite evaluated the risk of the escaped minks leading to the establishment of a viral reservoir in susceptible wildlife populations. This work provides guidance to Members on this newly emerging threat.

The next frontier: assessing the feasibility of eradicating mammalian pests from Auckland Island. (Special Issue: Restoration of New Zealand subantarctic islands.)

Auckland Island, the fifth largest island in New Zealand, is the only island in New Zealand's subantarctic region where introduced mammalian pests remain (pigs, Sus scrofa;mice, Mus musculus;cats, Felis catus). The island has unique biodiversity and is a key site for progressing New Zealand's goal to be free of several introduced predators by 2050. Recent island eradication successes have rekindled interest in eradicating pests from Auckland Island, and for the first time considering all three pests in one project. Over a 3-year period, we tested the feasibility of eradicating pigs, mice and cats by looking at what it would take to succeed, rather than what we could practically deliver with the tools we currently have. We proposed adaptations to current methods and used an evidence-based approach by undertaking large-scale field trials to test uncertainties and emerging technologies in-situ. We gathered data and evaluated proposed methods against five established principles of eradication while considering the logistics and infrastructure requirements of the project. Eradicating pigs, mice and cats from Auckland Island is worthwhile and feasible but dependent on further development of emerging technologies and capabilities for efficient delivery with an acceptable level of risk. Three eradication operations are required with specific sequencing and timing, supported by initial establishment of infrastructure. The project needs a large investment spread over 8 to 10 years to yield permanent and internationally important benefits with low ongoing cost to sustain. The feasibility study exposed the project's scale and was used to inform decision makers, who postponed the work in 2020 in response to the economic impacts of COVID-19. The study focusses future preparations on identified planning issues and dependencies to progress project readiness in anticipation of it being launched when economic conditions allow.

Detection of SARS-CoV-2 in a free ranging leopard (Panthera pardus fusca) in India.

We report an incidence of natural infection of SARS-CoV-2 in free-ranging Indian leopard (Panthera pardus fusca). The case was detected during routine screening. Post-mortem and laboratory examination suggested virus-induced interstitial pneumonia. Viral genome could be detected in various organs including brain, lung, spleen, and lymph nodes by real-time PCR. Whole-genome sequence analysis confirmed infection of Pango lineage B.1.617.2 of SARS-CoV-2. Till now, only Asiatic lions have been reported to be infected by SARS-CoV-2 in India. Infections in animals were detected during peak phase of pandemic and all the cases were captive with close contacts with humans, whereas the present case was observed when human cases were significantly low. No tangible evidence linked to widespread infection in the wild population and the incidence seems to be isolated case. High nucleotide sequence homology with prevailing viruses in humans suggested spillover infection to the animal. This report underlines the need for intensive screening of wild animals for keeping track of the virus evolution and development of carrier status of SARS-CoV-2 among wildlife species. Supplementary Information: The online version contains supplementary material available at 10.1007/s10344-022-01608-4.

Special Issue: Highlights of medical, urban and veterinary entomology. (Special Issue: Highlights of medical, urban and veterinary entomology.)

Life remained far from normal as we completed the first year of the Covid-19 pandemic and entered a second year. Despite the challenges faced worldwide, together we continue to move the field of Medical Entomology forward. Here, I reflect on parallels between control of Covid-19 and vector-borne disease control, discuss the advantages and caveats of using new genotyping technologies for the study of invasive species, and proceed to highlight papers that were published between 2020 and 2021 with a focus on those related to mosquito surveillance and population genetics of mosquito vectors.

Significance of nondomestic animals in 21st century epidemics

The risk of a new epidemic zoonosis is very high as shown by the experience with COVlD-19 and, more recently, by monkeypox spreading in Europe. The aim of this article is to present a brief analysis of those increasing threats, within the frame of One Health approach. As history shows, wild animals have been always considered as a potential threat to public health. First, we went back to "Black Death" (Plaque), pandemic of XIV century, caused by Yersinia pestis transmitted by fleas rats, that killed one third of European population. We also recalled AIDS pandemic, which, similarly to SARS or MERS, begun with virus transmission from exotic animals and has spread to western countries leading to numerous fatal cases in humans. Environmental changes, including climate alterations, globalization, anthropopressure of wildlife habitat are nowadays considered as the major drivers of facilitated dissemination of infectious diseases. Zoonoses represent 75% of all human diseases. Some of the most important reservoirs for zoonotic diseases are rodents and bats, while blood-sucking arthropods are important vectors of emerging diseases.